Table 5.
Adjusted mean changes in laboratory parameters during exposure period from baseline by sex
|
Laboratory test |
Adjusted Women |
Adjusted Men |
||||
|---|---|---|---|---|---|---|
| Mean | (95%CI) | p-value | Mean | (95%CI) | p-value | |
| ΔTG (mmol/L) | ||||||
| CCB |
-0.076 |
(-0.178, 0.025) |
0.3449 |
-0.061 |
(-0.162, 0.039) |
0.8484 |
| ARB |
-0.007 |
(-0.108, 0.095) |
|
-0.047 |
(-0.148, 0.053) |
|
| ΔTC (mmol/L) | ||||||
| CCB |
-0.127 |
(-0.239, -0.014) |
0.2907 |
-0.117 |
(-0.19, -0.044) |
0.9665 |
| ARB |
-0.214 |
(-0.326, -0.101) |
|
-0.115 |
(-0.188, -0.042) |
|
| ΔBlood glucose (mmol/L) | ||||||
| CCB |
-0.17 |
(-0.593, 0.253) |
0.6908 |
-0.152 |
(-0.505, 0.202) |
0.8447 |
| ARB |
-0.293 |
(-0.717, 0.131) |
|
-0.101 |
(-0.454, 0.252) |
|
| ΔHbA1c (%) | ||||||
| CCB |
-0.075 |
(-0.216, 0.066) |
0.0777 |
-0.092 |
(-0.201, 0.016) |
0.9247 |
| ARB |
-0.257 |
(-0.398, -0.116) |
|
-0.1 |
(-0.208, 0.009) |
|
| ΔCreatinine (μmol/L) | ||||||
| CCB |
0.475 |
(-0.776, 1.726) |
0.0592 |
2.346 |
(-0.967, 5.658) |
0.923 |
| ARB |
2.202 |
(0.948, 3.456) |
|
2.578 |
(-0.73, 5.886) |
|
| ΔSodium (mmol/L) | ||||||
| CCB |
-0.09 |
(-0.434, 0.254) |
0.1124 |
-0.279 |
(-0.567, 0.009) |
0.3479 |
| ARB |
-0.49 |
(-0.835, -0.145) |
|
-0.082 |
(-0.37, 0.206) |
|
| ΔPotassium (mmol/L) | ||||||
| CCB |
-0.015 |
(-0.067, 0.038) |
0.0188 * |
0.0002 |
(-0.041, 0.041) |
0.2423 |
| ARB |
0.075 |
(0.023, 0.128) |
|
0.035 |
(-0.006, 0.076) |
|
| ΔALT (U/L) | ||||||
| CCB |
-0.921 |
(-3.478, 1.636) |
0.1991 |
-0.31 |
(-2.767, 2.147) |
0.5436 |
| ARB |
-3.32 |
(-5.883, -0.758) |
|
-1.393 |
(-3.847, 1.06) |
|
| ΔAST (U/L) | ||||||
| CCB |
1.125 |
(-1.37, 3.621) |
0.0796 |
0.59 |
(-1.334, 2.514) |
0.6034 |
| ARB |
-2.43 |
(-4.931, 0.072) |
|
-0.135 |
(-2.057, 1.786) |
|
| ΔGGT (U/L) | ||||||
| CCB |
-1.498 |
(-6.821, 3.824) |
0.3965 |
3.176 |
(-6.48, 12.832) |
0.3908 |
| ARB |
-4.794 |
(-10.129, 0.541) |
|
-2.839 |
(-12.482, 6.804) |
|
| ΔWBC (x109/L) | ||||||
| CCB |
-0.092 |
(-0.278, 0.094) |
0.3973 |
-0.02 |
(-0.191, 0.152) |
0.7449 |
| ARB |
0.023 |
(-0.164, 0.209) |
|
-0.06 |
(-0.232, 0.111) |
|
| ΔRBC (x1012/L) | ||||||
| CCB |
-0.025 |
(-0.061, 0.012) |
0.0004 * |
-0.032 |
(-0.067, 0.003) |
0.0286 * |
| ARB |
-0.12 |
(-0.157, -0.083) |
|
-0.088 |
(-0.123, -0.053) |
|
| ΔPLT(x109/L) | ||||||
| CCB |
4.675 |
(-0.389, 9.738) |
0.2057 |
4.86 |
(0.551, 9.17) |
0.3242 |
| ARB |
-0.008 |
(-5.083, 5.067) |
|
1.776 |
(-2.528, 6.08) |
|
| ΔHemoglobin (g/L) | ||||||
| CCB |
-1.286 |
(-2.417, -0.156) |
0.0135 * |
-1.811 |
(-2.931, -0.692) |
0.2222 |
| ARB |
-3.333 |
(-4.466, -2.2) |
|
-2.804 |
(-3.922, -1.686) |
|
| ΔHematocrit (mmol/mol) | ||||||
| CCB |
-0.002 |
(-0.006, 0.001) |
0.0076 * |
-0.003 |
(-0.006, 0.0004) |
0.0796 |
| ARB | -0.009 | (-0.012, -0.005) | -0.007 | (-0.01, -0.004) | ||