Table 1.
Patient Demographics and MDS Disease Characteristics
| Age (years) | |
|---|---|
| Median (range) |
75 (57−82) |
|
Age (years) |
N (%) |
| < 65 years |
5 (26) |
| ≥ 65 years |
14 (74) |
|
Gender | |
| Male |
14 (74) |
| Female |
5 (26) |
|
ECOG Performance Status | |
| 0 |
13 (68) |
| 1 |
6 (32) |
|
IPSS Classification | |
| Low Risk |
5 (26) |
| Intermediate-1 Risk |
14 (74) |
|
Baseline Cytogenetics | |
| Normal |
14 (74) |
| Abnormal |
4 (21) |
| Unknown |
1 (5) |
|
Transfusion Dependency | |
| RBC Transfusion Dependent |
13 (68) |
| Median (Range) |
6 (4−10) |
| Platelet Transfusion Dependent |
2 (11) |
|
WHO Classification | |
| RA |
4 (21) |
| RAEB-1 |
2 (11) |
| RCMD |
4 (21) |
| RCMD-RS |
5 (26) |
| MDS-U |
3 (16) |
| MDS/MPD-U |
1 (5) |
|
Cell Lineage Cytopenia | |
| Unilineage Cytopenia |
9 (47) |
| Bilineage Cytopenia |
6 (32) |
| Trilineage Cytopenia |
4 (21) |
|
Baseline Cytopenia(s) | |
| Anemia only |
9 (47) |
| Anemia + Neutropenia |
1 (5) |
| Anemia + Thrombocytopenia |
5 (26) |
| Anemia + Neutropenia + Thrombocytopenia |
4 (21) |
|
Time from MDS Diagnosis (years) | |
| Median (range) | .9 (.10 − 2.5) |
Abbreviations: ECOG Eastern Cooperative Oncology Group; IPSS International Prognostic Scoring System; RBC red blood cell; RA refractory anemia; RAEB-1 RA with excess blasts, type 1; RCMD refractory cytopenia with multilineage dysplasia; RCMD-RS RCMD with ringed sideroblasts; MDS-U myelodysplastic syndrome-unclassified; MDS/MPN-U MDS/myeloproliferative neoplasm-unclassified.