Table 1. Demographic and clinical characteristics of the whole group of AA and CA patients and the subgroup with available brain volume measures.

All Patients (n = 194)	AA Patients	CA Patients
Male/Female	19/97 (19.6%)	19/97 (19.6%)
Age at onset (yrs)	33.5±10.6	33.2±10.0
Age at MRI (yrs)	42.7±11.6	42.4±10.8
Disease Duration (yrs)	9.1±7.2	9.5±7.5
Patients under treatment	79/97 (81.4%)	85/97 (85%)
Patients with SP-MS	24/97 (24.7%)	11/97 (11.3%)*
Patients with ambulatory assistance	28/97 (28.9%)	11/97 (11.3%)**

^*p = 0.04 (Fisher exact test); **p<0.01 (binary logistic regression analysis adjusted for age, gender, disease duration treatment type and exposure).