Table 3. Lesion and brain volume measures in whole MS patients stratified by ambulatory status, in CA MS and in AA patients stratified byambulatory status.

MRI	All patients	All patients	p value	CA patients	AA patients	p value	CA patients	AA patients	p value
	w/o aid	with aid		w/o aid	w/o aid		with aid	with aid
CELs	0.21±0.80	1.10±3.89	0.08	0.14±0.53	0.29±1.04	0.6	0.09±0.30	1.50±4.54	0.3
T2 LV	7.71±10.29	20.19±21.99	<0.0001	6.29±8.45	9.49±12.03	0.03	12.89±11.35	23.06±24.54	0.4
T1 LV	0.66±1.16	1.95±2.98	<0.0001	0.50±0.96	0.86±1.35	0.02	0.79±1.10	2.40±3.37	0.02
T1/T2 LV	0.10±0.16	0.11±0.09	0.05	0.11±0.20	0.09±0.10	0.2	0.07±0.06	0.12±0.09	0.1
NBV	1577.16±111.52	1485.05±134.18	0.001	1575.2±118.5	1579.45±103.98	0.8	1441.97±159.35	1503.19±122.31	0.3
NWMV	741.05±63.60	709.91±68.48	0.02	745.45±62.45	735.93±65.20	0.5	693.86±77.15	716.67±65.55	0.5
NGMV	896.90±61.82	775.13±90.08	0.0008	829.75±78.80	975.24±89.72	0.1	748.10±99.70	786.52±80.58	0.4

CELs  =  contrast-enhancing lesions (number); LV  =  lesion volume (mL); NBV  =  normalized brain volume (mL); NWMV  =  normalized white matter volume (mL); NGMV  =  normalized gray matter volume. (mL).