Table 1. Experimental progress of blood pressure and blood glucose in diabetic eNOS knockout mice treated with riociguat (3 mg/kg/d), telmisartan (1 mg/kg/d), both (3 mg/kg/d and 1 mg/kg/d) or vehicle.

	Telmisartan	Riociguat	Riociguat + Telmisartan	Diabetic, vehicle	Control, vehicle
Systolic blood pressure [mmHg]
Baseline	116.4±2.4	114.1±2.4	117.7±2.4	118.6±2.0	122.3±2.3
	n = 17	n = 15	n = 13	n = 17	n = 14
Final	111.2±2.3	105.2±2.5*	105.0±3.2*	117.1±2.2	118.8±5.1
	n = 14	n = 14	n = 12	n = 14	n = 14

Values are given as means ± SEM. For comparisons, student's t test was used.

^*p<0.05 vs. diabetic vehicle.

Additionally non-diabetic eNOS knockout mice treated with vehicle were examined.