Table 1. Structural statistic for the 20 lowest energy structures of TbPin1.

Restraints for calculations
Total NOE restraints used	1918
Intraresidue (|i–j| = 0)	711
Sequential (|i–j| = 1)	453
Short-range (2≤|i–j|≤3)	195
Medium-range (4≤ |i–j|≤5)	103
Long-range (|i–j|>5)	456
Hydrogen bond restraints	35
Dihedral angle restraints (Φ and Ψ) a	187

^aDihedral angle restraints are generated by TALOS+ [41].

^bQuality of the ensemble of the 20 lowest-energy structures of TbPin1 was assessed by PROCHECK-NMR [61].