Figure 4. Altered variation of MAP, HR and locomotor activity in EsrCre/flox/TM mice under constant darkness.

MAP (A&B), HR (C&D) and locomotor activity (E&F) were recorded using radiotelemetry for consecutive 2 days under constant darkness. Black bars correspond to the period of darkness, and the gray bars indicate the period of subjective light under constant darkness. N = 5–6 in each group. Data are mean ± SE. *, p<0.05; **, p<0.01; ns, non-significant.