Skip to main content
. 2012 Jul 4;32(27):9410–9418. doi: 10.1523/JNEUROSCI.1041-12.2012

Figure 2.

Figure 2.

Locomotor activity was analyzed over a 21 h period between 3:00 and 12:00 P.M. in male and female mice aged P42–P56 from the PNE, SAC, and WATER groups. The lights-off period was from 7:00 P.M. to 7:00 A.M. A–F, Hourly (A, B) or cumulative (C–F) locomotor activity measurements are shown. Both male (A) and female (B) mice in the PNE group showed significantly higher locomotor activity compared to their counterparts in the SAC and WATER groups throughout the 21 h period of observation (A–C). Activity between the SAC and WATER groups was not significantly different. When the activity was analyzed separately for the two lights-on and one lights-off sessions (C–E), PNE group showed significant increases during the lights-off period (E) and during the lights-on period immediately following (F) but not preceding (D) the lights-off period. There were no significant differences between SAC and WATER groups nor between male and female mice within any given prenatal treatment group. ANOVA and multiple comparison tests were used to test statistical significance of the experimental effects (male, n = 10–15; female, n = 10–15).