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CLP-induced murine polymicrobial sepsis significantly increases plasma levels of VEGF. C57BL/6 female mice underwent CLP or remained as unoperated controls (four animals each). Plasma was collected after 18 h and VEGF levels were measured by ELISA. VEGF levels were increased fivefold when compared to unoperated controls (234 pg/mL ± 100 vs. 46 pg/mL ± 16; p < 0.05. Results expressed as the mean ± standard error of the mean (SEM).
