. Author manuscript; available in PMC: 2012 Aug 11.

Published in final edited form as: Circ Arrhythm Electrophysiol. 2009 Feb;2(1):63–71. doi: 10.1161/CIRCEP.108.811562

Table 2.

Summary of studies of the relation of LGE with arrhythmia

	Source	Number of Patients, study design	Finding
Ischemic Cardiomyopathy	Bello et al ⁵⁴	48, prospective cohort	Infarct size and surface area was greater in patients with monomorphic ventricular tachycardia inducible at electrophysiology study.
	Yan et al ⁵⁵	144, retrospective cohort	Mortality was higher in patients with greater peri-infarct zone extent to infarct extent ratio.
	Schmidt et al ⁵⁶	47, prospective cohort	Higher LGE defined tissue heterogeneity at the infarct periphery was predictive of induciblity at electrophysiology study.

Hypertrophic Cardiomyopathy	Teraoka et al ⁶⁰	59, prospective cohort	Presence and extent of LGE were directly correlated with the presence of non sustained ventricular tachycardia on Holter monitoring.
	Dimitro et al⁹⁹	47, prospective cohort	Patients with non-sustained ventricular tachycardia on Holter monitoring were more likely to exhibit LGE. The extent of scar was not significantly different between the two groups.
	Adabag et al ⁶¹	177, prospective cohort	Non sustained ventricular tachycardia was more common in patients with LGE, and patients with LGE had greater numbers of non sustained ventricular tachycardia episodes. The extent of scar was not significantly different between the two groups.

Non-Ischemic Cardiomyopathy	Nazarian et al ⁶⁴	26, prospective cohort	Predominance of scar distribution involving 26–75% of wall thickness predicted inducible ventricular tachycardia at electrophysiology study.
	Assomull et al⁶⁵	101, prospective cohort	Midwall fibrosis was present in 35% of patients and predicted the combined endpoint of all cause death or hospitalization.
	Wu et al ⁶⁶	65, prospective cohort	The presence of LGE predicted the composite endpoint of hospitalization for heart failure, appropriate ICD firing, and cardiac death.

ARVD	Tandri et al ³⁸	30, prospective cohort	The presence of LGE predicted inducible ventricular tachycardia at electrophysiology study.

Chagas Disease	Rochitte et al⁸⁰	51, retrospective cohort	LGE was present in 100% of patients with documented history of ventricular tachycardia.