Table 2.
Dopaminergic Augmentation of Contingency Management Treatment of Cocaine Dependence: Double-Blind Placebo-Controlled Trials
| Author | Publication Year |
Population | Medication | Behavioral intervention |
N | results |
|---|---|---|---|---|---|---|
| Poling | 2006 | Cocaine and opioid dependence receiving methadone | bupropion | Contingency management | 106 | Bupropion with contingency management more effective than bupropion alone |
| Schmitz | 2008 | Cocaine dependence | Levodopa-carbidopa | Voucher incentives, CBT, and clinical management | 161 | Levodopa with vouchers associated with abstinence and negative urine tests |
| Schmitz | 2010 | Cocaine | Levodopa-carbidopa | Contingency management of urine, attendance, or medication taking | 136 | Levodopa with CM-urine produced superior cocaine use outcomes, with effect moderated by medication compliance |