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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Psychoneuroendocrinology. 2012 Apr 10;37(10):1688–1699. doi: 10.1016/j.psyneuen.2012.02.018

Figure 3.

Figure 3

Neonatal male and female astrocytes isolated from P0/1 pups were incubated with 0, 1, 10 and 100ng/ml LPS for 4 h and measured for IL-1β mRNA (A), MD2 mRNA(B), CD14 mRNA (C) and TLR4 mRNA (D). There was a significant LPS dose response on IL-1β mRNA and TLR4 mRNA in both male and female astrocytes. Males produced a greater IL-1β mRNA response than females. There was a significant effect of LPS on CD14 mRNA but no difference between the sexes. There was no significant effect on MD2 except in males at the high dose of LPS. Data are expressed as mean ± SEM (n=6/gp). * P<0.05 between groups.