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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2012 Jun 12;18(8):1182–1190.e1. doi: 10.1016/j.bbmt.2012.06.002

Fig. 6. Effect of LBH589 and SAHA on cytokine production.

Fig. 6

B/c mice were lethally irradiated and transplanted with 5 × 106 TCD B6 BM cells with or without 1 × 106 T cells. Recipients were treated with PBS vehicle, SAHA (25mg/kg BW, daily treatment from day 0 to 7) or LBH589 (1.25mg/kg BW, QOD, from day 0 to 12) via i.p injection. Mice were sacrificed on day 13, and serum IFN-γ (A) and TNF-α (B) were analyzed by flow cytometric bead array. The data shown here are pooled from 2 replicate experiments (n = 8) with the same setting. ***p<0.001.