Table 3.
The Association of Pulse Pressure (PP) With Incident ESRD Among KEEP Participants With Chronic Kidney Disease
| PP, mm Hg | Patients, No. | Age- and Sex-Adjusted HR (95% CI) | Adjusteda HR (95% CI) | SBP-Adjustedb HR (95% CI) |
|---|---|---|---|---|
| <50 | 3458 | 1 [Reference] | 1 [Reference] | 1 [Reference] |
| 50–64 | 4973 | 1.39 (1.00–1.93) | 0.95 (0.67–1.33) | 0.79 (0.55–1.13) |
| 65–79 | 3357 | 2.26 (1.58–3.23) | 1.03 (0.71–1.48) | 0.71 (0.45–1.10) |
| ≥80 | 2166 | 4.80 (3.40–6.80) | 1.44 (1.00–2.07) | 0.76 (0.44–1.32) |
Abbreviations: ESRD, end-stage renal disease; HR, hazard ratio; KEEP, Kidney Early Evaluation Program; SBP, systolic blood pressure.
a
Adjusted for age, sex, race/ethnicity, insurance, access to physician, current smoking, diabetes mellitus, body mass index, baseline estimated glomerular filtration rate, albuminuria, and prevalent cardiovascular disease.
b
Further adjusted for SBP.