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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Biol Psychiatry. 2011 Jul 18;71(3):247–253. doi: 10.1016/j.biopsych.2011.05.019

Table 4.

Prediction of External Potential Validating Variables by the 2 Additive Genetic ASPD Factors

Genetic Factors Validator Variable Estimated
Effect Size
Robust X2 (df)
test for
Constrained
Model
p - value
Aggressive-disregard Age − 0.255 0.394
Disinhibition Age − 1.806 0.000
Factor 1=Factor 2 9.62 (1)* 0.002
Aggressive-disregard Neuroticism 0.159 0.000
Disinhibition Neuroticism 0.198 0.000
Factor 1=Factor 2 0.56 (1) 0.453
Aggressive-disregard Novelty Seeking 0.180 0.000
Disinhibition Novelty Seeking 0.613 0.000
Factor 1=Factor 2 66.8 (1) 0.000
Aggressive-disregard Conduct Disorder 0.480 0.000
Disinhibition Conduct Disorder 0.379 0.000
Factor 1=Factor 2 4.34 (1) 0.036
Aggressive-disregard Major Depression 0.236 0.000
Disinhibition Major Depression 0.418 0.000
Factor 1=Factor 2 10.23 (1) 0.001
Aggressive-disregard Cannabis
Dependence
0.485 0.000
Disinhibition Cannabis
Dependence
0.537 0.000
Factor 1=Factor 2 0.29 (1) 0.589
Aggressive-disregard Cocaine Dependence 0.504 0.000
Disinhibition Cocaine Dependence 0.695 0.000
Factor 1=Factor 2 2.7 (1) 0.100
Aggressive-disregard Alcohol Dependence 0.609 0.000
Disinhibition Alcohol Dependence 0.491 0.000
Factor 1=Factor 2 3.1 (1) 0.078
Aggressive-disregard Age of First Drink − 0.360 0.000
Disinhibition Age of First Drink − 0.243 0.000
Factor 1=Factor 2 5.2 (1) 0.022
Aggressive-disregard Maximum Drinks 0.585 0.000
Disinhibition Maximum Drinks 0.301 0.000
Factor 1=Factor 2 28.6 (1) 0.000
Aggressive-disregard Treatment (Alc) 0.687 0.000
Disinhibition Treatment (Alc) 0.427 0.000
Factor 1=Factor 2 8.3 (1) 0.004
Aggressive-disregard Educational Level − 0.298 0.000
Disinhibition Educational Level − 0.023 0.536
Factor 1=Factor 2 23.4 (1) 0.000

Notes: All analyses controlled for age and sex. The sample size for the “treatment (Alc)” was truncated due to missing values. All coefficient invariance tests were done in Mplus using the robust WLSMV chi-square difference test.

*

indicates Robust MLR chi-square difference test was used (for continuous Novelty Seeking factors).