TABLE 4.

Effects on iliac artery gene expression relative to the endogenous control genes, GAPDH, B-actin, and RPLP

	Diet				Status
	C/L	SPI	P	Adjusted Pa	Low-risk	High-risk	P
MCP-1	0.0277 ± 0.0035	0.0085 ± 0.0036	<0.0001	<0.0001	0.0147 ± 0.0036	0.0216 ± 0.0035	0.056
VCAM-1b,c	0.5147 ± 0.1245	0.5423 ± 0.1275	0.456	—	0.4545 ± 0.1292	0.6025 ± 0.1228	0.408
ICAM-1	0.0143 ± 0.0013	0.0072 ± 0.0013	<0.0001	<0.0001	0.0096 ± 0.0013	0.0118 ± 0.0013	0.161
IL-6d	0.0944 ± 0.0001	0.0470 ± 0.0001	<0.0001	<0.0001	0.0522 ± 0.0001	0.0892 ± 0.0001	0.047
CD68	0.1477 ± 0.0197	0.0482 ± 0.0202	0.001	<0.0001	0.0760 ± 0.0205	0.1199 ± 0.0195	0.183
CD3d	0.3148 ± 0.0004	0.1534 ± 0.0004	0.015	<0.0001	0.2238 ± 0.0004	0.2445 ± 0.0004	0.711
CD4	0.0308 ± 0.0039	0.0111 ± 0.0040	0.001	<0.0001	0.0187 ± 0.0041	0.0232 ± 0.0039	0.689
TCR-βd	0.0119 ± 0.0001	0.0079 ± 0.0001	0.956	—	0.0104 ± 0.0001	0.0093 ± 0.0001	0.290
ER-α	0.0069 ± 0.0005	0.0094 ± 0.0005	0.001	<0.0001	0.0086 ± 0.0005	0.0077 ± 0.0005	0.191
ER-βd,e	0.0098 ± 0.0097	0.0111 ± 0.0100	0.091	—	0.0122 ± 0.0100	0.0090 ± 0.0100	0.017

Data are mean expression ± SEM. GADPH, glyceraldehyde-3-phosphate dehydrogenase; RPLP, ribosomal protein, large P0; C/L, casein/lactalbumin; SPI, soy protein isolate; Low-risk, dominant social status; High-risk, subordinate social status; MCP-1, monocyte chemotactic protein-1; VCAM-1, cell adhesion molecule-1; ICAM-1, intercellular adhesion molecule-1; IL-6, interleukin-6; TCR-β, T-cell receptor-β; ER, estrogen receptor.

^aAdjusted P represents significance of SPI treatment on gene expression measures covarying for plaque size.

^bMean × 10^–5.

^cSE × 10^–6.

^dMean × 10^–2

^eSE × 10^–8.