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. 2011 Feb 2;96(4):981–988. doi: 10.1210/jc.2010-0015

Fig. 2.

Fig. 2.

Impact of monthly vitamin D dosing on 25(OH)D. Serum 25(OH)D increases promptly after 50,000 IU of either vitamin D2 or D3. This phenomenon is present not only after the first dose, but also after the third monthly dose with a quite comparable increase in mean 25(OH)D (A). As noted in panel B, the decline over 1 month is such that the serum 25(OH)D increased by only 1.4 ng/ml with vitamin D2 and 2.2 ng/ml with vitamin D3.