Figure 1.

Representative magnetic resonance (MR) and computed tomography (CT) images of the brain of Border Collies with neuronal ceroid lipofuscinosis. MR images were obtained using a 0.3-tesla system (AIRIS2-comfort, Hitachi Medical Corporation) in a 24-month-old dog under general anesthesia. CT images were obtained using a multislice CT system (ECLOS, Hitachi Medical Corporation) in another 24-month-old dog under general anesthesia. (a) MR T1-weighted image (TR/TE = 500/20 ms) of a transverse section at the level of the thalamus, (b) MR T2-weighted image (TR/TE = 4,000/120 ms) of a transverse section at the level of the thalamus, (c) MR T2-weighted image of a sagittal section, and (d) CT image of a transverse section at the level of the thalamus. These images show enlarged ventricles and dilated cerebral and cerebellar sulci, suggesting forebrain atrophy.