. Author manuscript; available in PMC: 2012 Aug 13.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2010 Oct 11;19(12):3150–3156. doi: 10.1158/1055-9965.EPI-10-0763

Table 3.

Associations between rs9642880 T allele and bladder cancer risk by strata of selected risk factors

	Non-Hispanic white		P	Chinese		P	Non-Hispanic white and Chinese
	Cases/controls	RR (95% CI)	P	Cases/controls	RR (95% CI)	P	RR (95% CI)	P
Age at diagnosis^a
Younger	270/317	1.35 (1.05–1.74)	0.021	305/272	1.13 (0.88–1.46)	0.34
Older	239/285	1.52 (1.16–2.00)	0.0021	236/263	1.27 (0.95–1.69)	0.10
P_interaction		0.57			0.52
Gender^a
Male	401/485	1.41 (1.17–1.70)	0.0031	429/412	1.20 (0.99–1.45)	0.058	1.31 (1.15–1.49)	0.00068
Female	108/117	1.68 (1.09–2.59)	0.019	112/123	1.35 (0.89–2.04)	0.15	1.50 (1.12–2.02)	0.0069
P_interaction		0.38			0.53		0.30
Smoking history^b
Never	95/217	1.74 (1.21–2.50)	0.0026	182/238	1.23 (0.91–1.68)	0.18	1.43 (1.13–1.81)	0.0026
Former	193/259	1.57 (1.18–2.09)	0.0021	76/86	1.44 (0.87–2.38)	0.15	1.54 (1.20–1.97)	0.00071
Current	221/106	0.98 (0.70–1.39)	0.93	283/211	1.12 (0.85–1.48)	0.48	1.06 (0.86–1.32)	0.58
P_trend		0.022			0.76		0.46
P_interaction		0.055			0.51		0.32
NSAID use
Nonusers	313/355	1.27 (1.01–1.62)	0.045
Users	190/245	1.58 (1.16–2.14)	0.0038
P_interaction			0.17
Stage/grade^a
Ta/G1–2^c	284/602	1.64 (1.32–2.03)
All other stage/grade^d	218/602	1.19 (0.95–1.50)

Adjusted for smoking.

Adjusted for age and gender.

“Low probability of progression” as defined by Kiemeney et al (14).

“High probability of progression” as defined by Kiemeney et al (14).