Table 2. Comprehension and information processing of GSTM1 genetic test results delivered online among smokers related to patients with lung cancer.
| Outcomes | Test result | ||
|---|---|---|---|
|
| |||
| GSTM1-present (lower risk) | GSTM1-missing (higher risk) | Difference | |
| Immediately after receiving genetic test results (online Session 2) | |||
| Accurate comprehension, n (%) | |||
| Accurate recall of test result | 22 (100) | 22 (100) | NS |
| Accurate interpretation of test result | 12 (55) | 22 (100) | χ2 = 12.94;df = 1; P < 0.001 |
| Acceptability of test information* | |||
| Believable | 1.23 (0.52) | 1.55 (0.60) | NS |
| Trustworthy | 1.27 (0.55) | 1.50 (0.60) | NS |
| Easy to understand | 1.32 (0.65) | 1.45 (0.60) | NS |
| Relevant | 1.32 (0.65) | 1.45 (0.60) | NS |
| Important | 1.23 (0.53) | 1.41 (0.59) | NS |
| Processing of genetic test – related information | |||
| Viewed strengths information page, n (%) | 11 (50) | 7 (32) | NS |
| Viewed weaknesses information page, n (%) | 10 (45) | 8 (37) | NS |
| Total no. of information pages viewed | 3.1 (2.6) | 2.6 (2.7) | NS |
| 6-mo Follow-up | |||
| Accurate comprehension, n (%) | |||
| Accurate recall of test result | 18 (100) | 16 (100) | NS |
| Accurate interpretation of test result | 10 (56) | 15 (94) | χ2 = 6.35; df = 1; P = 0.011 |
| Decisional outcomes | |||
| Regret decision to take genetic test† | 0 (0%) | 0 (0%) | NS |
| Satisfied with decision to take genetic test† | 17 (100%) | 16 (94%) | NS |
NOTE: Values represent means (SDs) unless otherwise indicated.
Abbreviation: NS, not significant.
*
Possible scores range from 1 to 7; lower scores indicate more positive and higher acceptability responses (e.g., 1 = believable), and higher scores indicate more negative responses or lower acceptability (e.g., 7 = unbelievable).
†
Measured using a seven-point scale (1 = strongly disagree, 7 = strongly agree); values shown are proportions who gave responses of 4 to 7, that is, who somewhat to strongly agreed with statement.