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. Author manuscript; available in PMC: 2012 Aug 13.
Published in final edited form as: Inflamm Bowel Dis. 2010 May;16(5):753–764. doi: 10.1002/ibd.21133

Figure 3. IEC from UC and CRC donors do not transduce a signal through the ERK, JNK, and p38 pathways after IL-13 exposure.

Figure 3

Freshly isolated IEC from A) unaffected regions, B) CD inflamed, C) UC inflamed, and D) colon tumors were rested for 4 h and stimulated with 50 ng/ml IL-13. Total cellular proteins were extracted from untreated and treated cells after various times (1, 2, 5, 10, 20, or 30 min depending on number of available cells) and fractionated by SDS-PAGE. Phosphorylated and total STAT6, ERK 1/2, JNK, and p38 were detected by immunoblot. Data shown is representative of 4 control, 3 CD, 3 UC, and 4 colon tumor samples.