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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Radiat Res. 2011 Dec 16;177(6):792–803. doi: 10.1667/rr1281.1

TABLE 3.

Theoretical (single-hit, multitarget) Fits to Survival Curves of NOS Knockdown Hematopoietic Progenitor (32D cl 3) Cells

siRNA D0 (Gy) n
Control 1.25 ± 0.05 3.9 ± 2.4
NOS1 1.48 ± 0.08 (*P < 0.05) 1.5 ± 0.5
NOS1 + 5 mM l-argininea 1.59 ± 0.10 (*P < 0.05) 1.4 ± 0.3
NOS2 1.27 ± 0.17 4.6 ± 3.3
NOS3 1.23 ± 0.13 3.1 ± 2.0

Notes. The uncertainties given are standard errors.

*

When compared with controls, significant differences were observed only with NOS1 knocked down, irrespective of the presence of l-arginine. Fits to survival curves are provided as Supplementary Material (http://dx.doi.org/10.1667/RR1281.1.S1).

a

Additions made to the culture medium 1 h prior to irradiation.