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Effects of drug treatments on basal synaptic transmission (I/O functions) in NonTg Vs 3xTg-AD mice (compared with effect in control aCSF before drug)
| Treatment | NonTg | 3xTg-AD |
|---|---|---|
| Dantrolene | No change | Significantly increased |
| FK506 | No change | No change |
| FK506 + Dantrolene | No change | Significantly increased |
| XeB | No change | No change |
| XeB + Dantrolene | No change | Significantly increased |
