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Comparison of the Sensitivity and Specificity of Single- and Dual-Targeted Microbubbles (MBs) in SCC-1 Flank Tumors
| Variable | MBEGFR | MBCD147 | MBDUAL |
|---|---|---|---|
| Sensitivity, % (95% CI) | 91 (88–95) | 93 (81–98) | 100 (100–100) |
| Specificity, % (95% CI) | 83 (77–91) | 79 (75–89) | 87 (83–95) |
| PPV, % | 91 | 93 | 100 |
| NPV, % | 85 | 82 | 89 |
Abbreviations: MBEGFR, MBCD147, and MBDUAL indicate anti-EGFR–, and anti-CD147–targeted MBs and dual-conjugated MBs, respectively; NPV, negative predictive value; PPV, positive predictive value.
