Table 2.

Results from a repeated measures general linear model (GLM) analysis of the variations in antibody levels

Dependent pair (pre- and post-treatment)	Time F (P)	Time*sex F (P)	Time*age F (P)	Time*village F (P)	Time*infection intensity F (P)	Time*PZQ treatment F (P)
Anti-schistosome responses
SWAP IgE	77·178 (<0·001)	0·040 (0·842) f<m	0·108 (0·898)	13·925 (<0·001)H > L	19·561 (<0·001)	5·558 (0·019)T > U
SWAP IgG4	49·485 (<0·001)	2·077 (0·15) f < m	11·024 (<0·001)	0·354 (0·552)H > L	26·952 (<0·001)	0·209 (0·648)T > U
SWAP IgE/IgG4	4·72 (0·031)	0·558 (0·455)f > m	1·778 (0·171)	0·095 (0·758)H > L	1·052 (0·306)	4·342 (0·038)T > U
SEA-IgE	5·00 (0·026)	1·315 (0·252)f < m	5·828 (0·003)	50·299 (<0·001)H > L	15·534 (<0·001)	3·193 (0·075)T < U
SEA-IgG4	0·323 (0·57)	0·279 (0·597)f < m	0·321 (0·726)	2·638 (0·105)H > L	6·086 (0·014)	2·368 (0·125)T > U
SEA-IgE/IgG4	2·070 (0·151)	0·44 (0·508) f > m	1·378 (0·254)	36·535 (<0·001)H < L	1·586 (0·209)	1·041 (0·308)T < U
Anti-allergen responses
Derp1-IgE	47·238 (<0·001)	6·281 (0·013)f > m	6·939 (0·001)	6·382 (0·012)H < L	0·009 (0·926)	4·902 (0·028)T > U
Derp1-IgG4	42·278 (<0·001)	3·548 (0·061)f < m	13·72 (<0·001)	34·706 (<0·001)H < L	1·783 (0·183)	0·768 (0·382)T < U
Derp1-IgE/IgG4	34·963 (<0·001)	0·271 (0·603)f > m	4·347 (0·014)	15·063 (<0·001)H > L	3·786 (0·053)	3·414 (0·066)T < U

F (and P) values from repeated measures GLM analysis of the parameters explaining the variations in antibody responses (and ratios) over time (time here stands for the 6 weeks between pre- and post-treatment collection day). Significant P-values <0·05 are highlighted in bold. SWAP, soluble worm antigen preparation; SEA, soluble egg antigen; Derp1, Dermatophagoides pteronyssinus allergen 1; PZQ, praziquantel; f, female; m, male; H, high infection area; L, low infection area; T, treated; U: untreated.