Table 1.

Reviewed omics studies in Brucella pathogenesis and host immunity.

Brucella spp.	Host cells and spp.	Temporal	Reference
COMPARATIVE BRUCELLA GENOMICS ANALYSIS BASED ON SEQUENCE BIOINFORMATICS ANALYSIS
B. abortus, B. melitensis, B. suis	–	No	Ratushna et al. (2006)
6 classical Brucella species	–	No	Whatmore et al. (2007)
BRUCELLA GENOME ANALYSIS USING WET-LAB BRUCELLA GENOMIC MICROARRAY
B. melitensis	–	No	Rajashekara et al. (2004)
BRUCELLA TRANSCRIPTOMIC PROFILES USING DNA MICROARRAY
B. melitensis	–	No	Viadas et al. (2009)
B. melitensis	–	Yes	Rossetti et al. (2009)
WT and bvrR B. abortus mutant	–	No	Viadas et al. (2010)
WT and vjbR B. melitensis mutant	–	No	Weeks et al. (2010)
WT and blxR B. melitensis mutant	–	No	Rambow-Larsen et al. (2008)
BRUCELLA PROTEOMIC PROFILES USING PROTEOMICS MICROARRAY
B. abortus S2308 and S19	In mouse macrophages	Yes	Lamontagne et al. (2009)
B. suis	In mouse macrophages	No	Al Dahouk et al. (2008)
B. melitensis	In HeLa cells	Yes	Rossetti et al. (2011)
B. melitensis	In human sera	No	Liang et al. (2011)
B. melitensis	In goat and human sera	No	Liang et al. (2010)
BRUCELLA-INFECTED HOST TRANSCRIPTOMIC PROFILES USING DNA MICROARRAY
B. abortus	Mouse macrophages	No	Eskra et al. (2003)
B. melitensis	Mouse macrophages	Yes	He et al. (2006)
B. melitensis, B. neotomae, B. ovis	Mouse macrophages	No	Covert et al. (2009)
B. suis	Mouse macrophages	Yes	Chen et al. (2011)
B. abortus	Cattle macrophages	No	Rossetti et al. (2010)
B. abortus	Bovine trophoblastic cells	No	Carvalho Neta et al. (2008)
B. abortus, B. melitensis, virB mutants	Mouse spleens	No	Roux et al. (2007)
B. suis biovar 2	Eurasian wild boar spleens	No	Galindo et al. (2010)
Rough B. ovis strain PA	Ram buffy coat	Yes	Galindo et al. (2009a)
B. melitensis strain Rev 1	Ram buffy coat	Yes	Galindo et al. (2009b)