Table 2.
Providers of kinase panel profiling services
| Provider | Location of profiling lab | Technology | Kinase panel size (wild-type kinases) | Website |
|---|---|---|---|---|
| Carna Biosciences | Kobe, Japan | Substrate mobility shift assay | 305 (272) | http://www.carnabio.com |
| DiscoverX (Ambit) | San Diego, CA, USA | Phage display competitive binding | 451 (394) | http://www.kinomescan.com |
| Millipore | Dundee, UK | Radioactive filter binding | 299 (261) | http://www.millipore.com |
| Life Technologies | Madison, WI, USA and Paisley, UK | Z'-Lyte™ and Adapta® binding assay | 317 (293) | http://www.invitrogen.com |
| ProQinase | Freiburg, Germany | Radioactive filter binding | 340 (298) | http://www.proqinase.com |
| Reaction Biology | Malvern, PA, USA | Radioactive filter binding | 385 (348) | http://www.reactionbiology.com |
| MRC Centre for Kinase Profiling | Dundee, UK | Radioactive filter binding | 126 (122) | http://www.kinase-screen.mrc.ac.uk |
Kinase panel sizes as reported on November 2011. The order of suppliers is alphabetical. The authors have had compounds profiled with most of the listed labs, and obtained robust data from all of them. See provider's websites for more information on technologies and protocols used.