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Aortic ALE levels and oxidative stress. Immunohistochemistry of aortic sinus from representative untreated and D-carnosine octylester-treated ApoE null mice fed a HFD and quantification of expression (mean ± SD; n= 5 per group) for HNE adducts (panel A), oxLDLs (panel B) and nitrotyrosine (panel C); scale bar = 100 µm. *P < 0.001 or †P < 0.01 versus the untreated mice. L = lumen; DCO = D-carnosine octylester.
