Figure 5.
Effect of i.p. injected CBC (10 and 20 mg·kg−1) and of the psychotropic cannabinoid receptor agonist WIN 55,212-2 (1 mg·kg−1) on upper gastrointestinal transit (A), colonic propulsion (B) and whole gut transit in mice (C) (see Methods for details concerning the measurement of motility). Columns represent the mean ± SEM of 6–11 mice for each experimental group **P < 0.01 versus control. Note that a decreased transit is indicated by a decreased value of GC (A), by an increased value of ‘time of expulsion (min)’ (B) or by an increased time of ‘whole gut transit (min)’ (C).