Skip to main content
. 2012 Jun;166(4):1474–1489. doi: 10.1111/j.1476-5381.2012.01889.x

Figure 3.

Figure 3

Exogenously added N-acylethanolamines partially reverse Aβ-induced inflammation in WT astrocytes by reducing the increase in the expression levels of iNOS (A), COX-2 (B) and TNF-α (C). Astrocytes were incubated with AEA, PEA or OEA (10 µM each), alone or in combination, for 24 h and then exposed to Aβ (AB) for 8 h. iNOS, COX-2 and TNF-α mRNAs were quantified by qRT-PCR. Results shown are the mean ± SEM of three independent experiments performed in triplicate. Data were analysed by one-way anova (***P < 0.001 vs. control; #P < 0.05, ##P < 0.01 and ###P < 0.001 vs. Aβ). COX-2: F (31.2/2), P = 0.00001. iNOS: F (54.7/2.1), P = 0.00001. TNF-α: F (19.9/2.1), P = 0.00001.