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Regional and cellular expression of HCN channel proteins in the sino-atrial node. Left, sections through the SAN region of C57BL/6 mice stained with antibodies directed against HCN1, HCN2 and HCN4 as indicated. * denotes significant HCN2 positive cells. Right, sino-atrial cells isolated from C57BL/6 mice labelled with the HCN4 antibody. Representative examples of spider, spindle and elongated spindle cells are shown. SA, sino-atrial node artery.
