Table 2.

Regional differences of MAP duration (MAP₉₀; ms) after infusion of erythromycin (E) and after additional infusion of verapamil (V) in failing hearts

CL (ms)	LV (MAP90; ms)	RV (MAP90; ms)	Endo (MAP90; ms)	LV difference (ms)	Endo difference (ms)
Baseline
900	189 ± 28	194 ± 21	191 ± 42
800	188 ± 26	193 ± 27	187 ± 28
700	184 ± 25	191 ± 21	186 ± 29
600	177 ± 25	183 ± 18	188 ± 29
500	168 ± 21	174 ± 13	168 ± 21
400	155 ± 15	162 ± 17	156 ± 14
300	134 ± 17	139 ± 11	135 ± 11
300 µM E				Prolongation to base	Prolongation to base
900	244 ± 29*	256 ± 27*	283 ± 25*	+55	+92¥
800	233 ± 26*	245 ± 29*	277 ± 31*	+46	+90¥
700	225 ± 22*	237 ± 28*	267 ± 25*	+41	+80¥
600	213 ± 26*	225 ± 23*	246 ± 28*	+35	+58¥
500	198 ± 25*	211 ± 25*	230 ± 26*	+30	+62¥
400	176 ± 28*	190 ± 22*	204 ± 23*	+21	+48¥
300	149 ± 21*	161 ± 20*	168 ± 21*	+15	+32¥
300 µM E + 0.75 µM V				Shortening to 300 µM E	Shortening to 300 µM E
900	178 ± 21#	177 ± 28#	207 ± 27#	−66	−76ж
800	170 ± 29#	166 ± 21#	188 ± 25#	−64	−89ж
700	160 ± 22#	156 ± 27#	169 ± 23#	−65	−98ж
600	151 ± 24#	150 ± 23#	156 ± 11#	−61	−89ж
500	141 ± 19#	140 ± 21#	141 ± 18#	−57	−89ж
400	127 ± 15#	126 ± 18#	129 ± 16#	−49	−75ж
300	112 ± 15#	114 ± 15#	112 ± 14#	−37	−56ж

LV left ventricle; RV, right ventricle.

^*P < 0.05, significantly different from baseline;

^#P < 0.05, significantly different from erythromycin-treated hearts;

^¥P < 0.05, significantly different from prolongation in LV;

^жP < 0.01, significantly different from shortening in LV.