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. 2012 May;166(2):602–616. doi: 10.1111/j.1476-5381.2011.01782.x

Figure 7.

Figure 7

Effect of EC18 on the slow diastolic depolarization in dog Purkinje fibres. (A) Action potentials recorded in dog Purkinje fibres in the absence and presence of 1 and 10 µM EC18. (B) Amplitude (mean ± SEM) of spontaneous diastolic depolarization recorded in the absence and presence of 1, 3 and 10 µM EC18. (C) Steepness (mean ± SEM) of diastolic depolarization phase, indicated by the first derivative (dV/dt) of the membrane voltage calculated in the absence and presence of 1, 3 and 10 µM EC18. n= 5, *P < 0.05.