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The Wiggers diagram illustrates the synchronization of the electrical (ECG) and mechanical (left ventricular pressure, LVP) activity of the cardiac muscle in anaesthetized guinea pigs. The E-M window is defined as the delay between the duration of the electrical (QT interval) and mechanical (QLVPend interval) systole. E-M window = QLVPend interval – QT interval. BP, blood pressure.
