Table 1.

Comparison of estimated binding affinities (pK_i values) of JK-P compounds to VEGFR2, FGFR1 and FGFR3 kinase domains in silico, as predicted using SPROUT programme (see Methods section)

	Estimated pKi
Compound	VEGFR2	FGFR1	FGFR3
JK-P3	−8.44	−6.94	−8.71
JK-P5	−9.16	−7.29	−9.01