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Stimulation of complement C3b formation in human plasma by mAbs CS-D7, CS-D7·N297A, or Rituxan©. Microtiter plates coated with one of three mAbs were exposed to C1q serially diluted into C1q deficient human sera. C3b generation was quantitated as described in Methods. Data shown are the mean ± s.e. n = 3.
