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Passive immunization and challenge of FcγII−/− mice.
| mAb | Number of FcγII−/− mice surviving Hours post challenge | Total (%) | P | ||||
|---|---|---|---|---|---|---|---|
| 0 | 24 | 48 | 72 | 96 | |||
| CS-D7 | 20 | 19 | 16 | 16 | 11 | 11 (55%) | *0.01 |
| CS-D7·N297A | 20 | 16 | 14 | 11 | 9 | 9 (45%) | †0.34 |
| 20C2HA | 20 | 14 | 9 | 6 | 5 | 5 (25%) | |
Comparison of survival with CS-D7 versus survival with isotype control 20C2HA.
Comparison of survival with CS-D7·N297A versus survival with CS-D7.
