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Passive immunization and challenge of complement deficient mice.
| mAb | Number of complement deficient mice surviving Hours post challenge | Total (%) | P | ||||
|---|---|---|---|---|---|---|---|
| 0 | 24 | 48 | 72 | 96 | |||
| CS-D7 | 25 | 15 | 6 | 6 | 2 | 2 (8%) | *0.097 |
| CS-D7·N297A | 25 | 11 | 7 | 5 | 0 | 0 (0%) | †0.33 |
| 20C2HA | 25 | 9 | 5 | 3 | 0 | 0 (0%) | |
*Comparison of survival with CS-D7 versus survival with isotype control 20C2HA.
†Comparison of survival with CS-D7·N297A versus survival with CS-D7.
