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Passive immunization and challenge of P47 phox−/− (neutrophil impaired) mice.
| mAb | Number of P47 phox−/− mice surviving Hours post challenge | Total (%) | P | ||||
|---|---|---|---|---|---|---|---|
| 0 | 24 | 48 | 72 | 96 | |||
| CS-D7 | 10 | 10 | 6 | 3 | 1 | 1 (10%) | *0.95 |
| CS-D7·N297A | 10 | 10 | 4 | 3 | 2 | 2 (20%) | †0.95 |
| 20C2HA | 10 | 10 | 4 | 3 | 2 | 2 (20%) | |
*Comparison of survival with CS-D7 versus survival with isotype control 20C2HA.
†Comparison of survival with CS-D7·N297A versus survival with CS-D7.
