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. 2012 May 4;2:59. doi: 10.3389/fcimb.2012.00059

Table 1.

Leishmania infection outcomes following neutrophil depletion in vivo.

Mouse strain Leishmania strain Site and route of infection Antibody Outcome References
C57BL/6 L. major Footpad (sc) RB6-8C5 Increase parasite load in dLN 6 h, 24 h, 16 d, and 29 d p.i. Lima et al. (1998)
C57BL/6 L. major Footpad (sc) NIMP-R14 Increase parasite load in footpad 35 d p.i.; no difference 65 d p.i. Tacchini-Cottier et al. (2000)
C57BL/6 L. major Footpad (sc) RB6-8C5 Increase parasite load in dLN 10 d p.i. Ribeiro-Gomes et al. (2004)
C57BL/6 L. major Ear Sand fly RB6-8C5 Decrease parasite load in ear 2 and 4 weeks p.i. Peters et al. (2008)
C57BL/6 L. donovani iv RB6-8C5 Increase parasite load in spleen and liver 14 d p.i. Smelt et al. (2000)
BALB/c L. major Footpad (sc) RB6-8C5 No difference in dLN 24 h, 16 d, and 29 d p.i. Lima et al. (1998)
BALB/c L. major Footpad (sc) NIMP-R14 Decrease parasite load in footpad 35 d p.i. Tacchini-Cottier et al. (2000)
BALB/c L. major Footpad (sc) RB6-8C5 Decrease parasite load in dLN 10 d p.i. Ribeiro-Gomes et al. (2004)
BALB/c L. major Footpad (sc) RB6-8C5 Increase parasite load in footpad 11 weeks p.i. Chen et al. (2005)
BALB/c L. donovani iv RB6-8C5 Increase parasite load in spleen and liver 14 d p.i. Smelt et al. (2000)
BALB/c L. donovani iv NIMP-R14 Increase parasite load in spleen and bone-marrow 14 d p.i. McFarlane et al. (2008)
BALB/c L. braziliensis Ear (id) RB6-8C5 Increase parasite load in ear and dLN 14 d p.i. Novais et al. (2009)
BALB/c L. infantum iv RB6-8C5 Increase parasite load in spleen 22 d p.i. Rousseau et al. (2001)
BALB/c L. infantum Ear (id) RB6-8C5 Decrease parasite load in ear; increase in dLN 1 d p.i. Thalhofer et al. (2011)
C3H/HeJ L. major Footpad (sc) RB6-8C5 No difference in lesion size Chen et al. (2005)

sc, subcutaneous; iv, intravenous; id, intradermal; p.i., post-infection.