Table 2.

Summary of CC30 strains and genotypic data.

CLADE:
													ISSau2e
Isolatea	PRJNAb	Year	Country	Genotype	SCCmec	PVLd	agrC	hla	isdH	trpG	TA-module	SaPI	trpS	rRNA-3	rplQ	sbcCf	saeRS
CLADE 1:
55/2053	55909	1955	England	ST30spa43	MSSA	P	Gly55	CAGGln	CAAGln	6TG	P	SaPI1	P		A	A	A
58–424	47005	1958	GA, USA	ST30spa43	MSSA	P	Gly55	CAGGln	CAAGln	6TG	P	SaPI1	P	P	A	A	A
E1410	55915	1962	Denmark	ST30spa43	MSSA	A	Gly55	CAGGln	CAAGln	6TG	P	SaPI1	P		A	A	A
M1015c	47009	1962	Australia	ST30spa43	MSSA	P	Gly55	CAGGln	CAAGln	6TG	P	SaPI1	P	P	A	A	A
M876	55917	1961	Australia	ST30spa43	MSSA	P	Gly55	CAGGln	CAAGln	6TG
M809	47007	1961	Australia	ST431spa43	MSSA	P	Gly55	CAGGln	CAAGln	6TG	P	SaPI1	P	P	A	A	A
M899	42993	1961	Australia	ST30spa43	MSSA	P	Gly55	CAGGln	CAAGln	6TG	P	SaPI1	P		A	A	A
65–1322	55911	1965	WV, USA	ST30spa43	MSSA	P	Gly55	CAGGln	CAAGln	6TG	P	SaPI1	P		A	A	A
68–397	55913	1968	TX, USA	ST30	MSSA	P	Gly55	CAGGln	CAAGln	6TG	P	SaPI1	P		A	A	A
C101	43001	1997	England	ST30spa43	MSSA	A	Gly55	CAGGln	CAAGln	6TG	P	SaPI1	P		A	A	A
CLADE 2:
WBG10049c	42991	1999	Australia	ST30spa19	IV	P	Gly55	CAGGln	CAAGln	6TG	P	SaPI1	P	P	A	A	A
TCH60	CP002110		TX, USA	ST30spa19	IV	P	Gly55	CAGGln	CAAGln	6TG	P	SaPI1	P	P	A	A	A
CLADE 3:
MN8c	59529	1980	MN, USA	ST30spa33	MSSA	A	Arg55	TAG*	TAA*	5TG	A	SaPI2, SaPI4	P	A	P	A	P
UAMS-1		1995	AR, USA	ST30spa33	MSSA	A	Arg55	TAG*	TAA*	5TG	A	SaPI2, SaPI4	P	A	P	A	A
Btn1260	42987	1999	England	ST30spa33	MSSA	A	Arg55	TAG*	TAA*	5TG	A	SaPI2, SaPI4	P	A	P	A	A
MRSA 252c	57839	1990's	England	ST36spa16	II	A	Arg55	TAG*	TAA*	5TG	A	SaPI4	P	A	P	P	A
EMRSA-16	48295	1990's	England	ST36spa16	II	A	Arg55	TAG*	TAA*	5TG	A	SaPI2, SaPI4	P	A	P	P	A
A017934/97	43393	1997	Sweden	ST30spa43	IV	A	Arg55	TAG*	TAA*	5TG	A	SaPI2, SaPI4	P	A	P	A	A
WW2703/97	42989	1997	Germany	ST30spa16	IV	A	Arg55	TAG*	TAA*	5TG	A	SaPI4	P	A	P	A	A

^aData for year, country, MLST, spa, SCCmec and PVL derived from [Robinson et al. (2005)], with exception of TCH60, MN8, and UAMS-1.

^bPublic domain whole genome sequencing project nucleic acid sequence accession number.

^cIncluded in genome comparisons conducted by SOLiD 3 sequencing and SNP analysis [DeLeo et al. (2011)].

^dDefined as present (P) or absent (A), as also for toxin-antitoxin module (TA) and SaPI elements.

^eISSau2 insertion sites defined in Figures 1 and 3.

^fSame distribution profile for ISSau2 insertions at sbcC, rRNA-1 and rRNA-2.