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. 2010 Jan;86(1):62–83. doi: 10.2183/pjab.86.62

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© 2010 The Japan Academy

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 8 — Enhanced F-actin nucleation by mDia1 around the sites of vigorous actin disassembly in live XTC cells (adopted from ref. ⁹⁾. Colocalization between the emergence site of the single-molecule mDia1 FH2 probe (circles), the catalytic core for its actin nucleation activity, and the distribution of AIP1 (mPlum-tagged; fluorescence image) is shown. AIP1 is a cofactor of cofilin and was used to monitor the distribution of cofilin-catalyzed actin disassembly. Scale bar, 5 μm. Adopted with permission from J. Cell Sci. 121, 3403–3412, Fig. 6 (2008).