Table 6.
Virulence-associated transcripts bound by cellular c-Myc-SarA.
| Common name* | Fold change† | mRNA stability‡ | Description |
|---|---|---|---|
| arcB | 8.3 | Stabilized | Ornithine carbamoyltransferase |
| pfoR | 3.7 | Destabilized | Perfringolysin O regulator protein |
| rsbW | 7.6 | Anti-sigma B factor | |
| SA0097 | 8.3 | Destabilized | Transcriptional regulator AraC/XylS family |
| sarZ | 2.7 | SarA homolog | |
| sbi | 3.3 | Destabilized | IgG-binding protein |
| spa | 4.2 | Stabilized | IgG-binding protein A |
| srtA | 7.4 | Sortase |
*S. aureus strain N315 locus.
†Fold change of signal intensities present in c-Myc-SarA samples in comparison to ΔsarA samples (p < 0.05).
‡Effect of sarA on transcript turnover.