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. 2011 Jun 1;1:10.3402/pba.v1i0.7202. doi: 10.3402/pba.v1i0.7202

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© 2011 Christina Pettan-Brewer and Piper M. Treuting

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 7 — Subclinical degenerative lesions diagnosed histologically. A. Decal cross-section of the nose and incisor roots (arrows) with unilateral multiple immature intrapulpal denticles from a 28-month-old B6 mouse. B. Higher magnification of the intrapulpal denticles. Denticles with an unusual presentation of a central column of ameloblasts (*) encircled with clear space, predentin (arrow, pink band) and odontoblasts (arrowhead). Denticles may represent dysplastic tooth development. Normal position of ameloblasts (*) and odontoblasts (arrow) are also indicated. C. Osteoarthritis of the temporomandibular joint from the mouse in A with incisor dysplasia. Mandibular condyle is indicated (*). D. Higher magnification of boxed region in C. The mandibular condyle and maxillary fossal cartilages are degenerative and irregular. The joint space (*) contains free floating debris and cartilage (joint mice).