Table 3.
Clinicopathological data from B6 mouse presented in Figures 2B, 5C, and 5D and CB6F1 mouse presented in 3B, 3D, and 4C
| B6 Female Figs. 2B and 5C,D | CB6F1 Male Figs. 3B,D and 4C | Reference valuesa | |
|---|---|---|---|
| Complete blood count | |||
| WBC, K/ul | 2.5 | 14.8 | 5.1–11.6 |
| RBC, M/ul | 8.5 | 11.1 | 8.7–10.5 |
| HGB, g/dl | 12.9 | 15.4 | 12.2–16.2 |
| HCT,% | 51.0 | 55.8 | 42–44 |
| MCV, fl | 60.1 | 50.1 | na |
| MCH, pg | 15.3 | 13.8 | na |
| MCHC | 0.3 | 27.6 | na |
| Platelet count, K/ul | 992.0 | 2043.0 | 100–1,000 |
| Differential | |||
| Absolute/µl (%) | Absolute/µl (%) | ||
| Bands | 0 (0.0) | 0 (0.0) | 0 |
| Polys | 960 (38.0) | 6,220 (42.0) | 6.7–37.2 |
| Lymph | 1,240 (49.0) | 7,090 (48.0) | 63–75 |
| Monos | 250 (10.0) | 1,030 (7.0) | 0.7–2.6 |
| Eos | 80 (3.0) | 440 (3.0) | 0.9–3.8 |
| Baso | 0 (0.0) | 0 (0.0) | 0–1.5 |
| Comments | Polychromasia, +1 | Slight polychromasia Platelet count inaccurate due to clumps | |
| Small mammal panel | |||
| Glucose mg/dl | 196.0 | 170.0 | 106–278 |
| Urea nitrogen (BUN), mg/dl | 24.0 | 30.0 | 19–34 |
| Calcium, mg/dl | 10.6 | 10.1 | 9–12 |
| Total protein, g/dl | 6.9 | 5.7 | 4.3–6.4 |
| Albumin, g/dl | 3.5 | 3.2 | 2.0–4.7 |
| Alanine aminotransferase, U/l | 43.0 | 47.0 | 26–120 |
| Aspartate aminotransferase, U/l | 83.0 | 107.0 | 69–191 |
| Principal histologic diagnoses | Pituitary adenocarcinoma Histiocytic sarcoma Keratitis and corneal ulceration Polyarteritis | Harderian gland adenoma Preputial adenitis and seminal vesiculitis Mild nephropathy | |