Table 3. Proportion of hospitals recording a change in the number of children aged under 5 years with IPD from 1998–1999 to 2006a that agreedb with the change recorded in their surveillance areas,c United States of America.
| IPD cases at each hospital | IPD caused by any serotype |
IPD caused by serotypes in PCV7d |
IPD caused by serotypes not in PCV7d |
|||||
|---|---|---|---|---|---|---|---|---|
| Hospitals in agreement/all hospitalse (No./no.) |
Hospitals in agreement (%) |
Hospitals in agreement/all hospitalse (No./no.) |
Hospitals in agreement (%) |
Hospitals in agreement/all hospitalse (No./no.) |
Hospitals in agreement (%) |
|||
| Annual average of cases in 1998 and 1999f | ||||||||
| 0 to 5 | 9/82 | 11 | 72/72 | 100 | 6/32 | 19 | ||
| 6 to 10 | 5/7 | 71 | 6/7 | 86 | 3/5 | 60 | ||
| 11 to 15 | 5/5 | 100 | 5/5 | 100 | 2/5 | 40 | ||
| 16 to 20 | 0/0 | NA | 0/0 | NA | 0/0 | NA | ||
| 21 to 25 | 2/3 | 67 | 3/3 | 100 | 3/3 | 100 | ||
| 26 to 30 | 0/1 | 0 | 1/1 | 100 | 1/1 | 100 | ||
| All | 21/98 | 21 | 87/88 | 99 | 15/46 | 31 | ||
| Proportion (%) of the surveillance area's cases during 1998 and 1999f | ||||||||
| 0–10 | 9/79 | 11 | 68/69 | 99 | 5/30 | 17 | ||
| 11–20 | 3/4 | 75 | 4/4 | 100 | 1/3 | 33 | ||
| 21–30 | 7/11 | 64 | 11/11 | 100 | 6/10 | 60 | ||
| 31–40 | 0/2 | 0 | 2/2 | 100 | 1/1 | 100 | ||
| 41–50 | 1/1 | 100 | 1/1 | 100 | 1/1 | 100 | ||
| 51–60 | 1/1 | 100 | 1/1 | 100 | 1/1 | 100 | ||
| All | 21/98 | 21 | 87/88 | 99 | 15/46 | 33 | ||
IPD, invasive pneumococcal disease; NA, not applicable; PCV7, seven-valent pneumococcal conjugate vaccine.
a PCV7 was introduced in the United States in 2000.
b The change in the number of hospitalized cases of IPD in children aged under 5 years from the average in 1998 and 1999 to 2006 was judged to be in agreement with the change observed in the corresponding surveillance area when the magnitude of the change in the number recorded at the hospital fell within the 95% confidence interval of the magnitude of the change in the incidence of hospitalized IPD cases for the corresponding surveillance area.
c Areas covered by the Active Bacterial Core surveillance system.
d PCV7 includes Streptococcus pneumoniae serotypes 4, 6B, 9V, 14, 18C, 19F and 23F.
e The denominators vary across the columns because some sentinel hospitals either did not have any IPD cases caused by serotypes in PCV7 or did not have any cases caused by serotypes not in PCV7 in 1998 or 1999.
f P < 0.01 for trend (Cochran-Armitage test) for IPD caused by any serotype and for IPD caused by serotypes not in PCV7.