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Crystal structure of the START domain of CERT.43) (A) The apo-form of the CERT START domain in a ribbon representation. α-Helices (α1-α4), β-strands (β1-β9), and Ω loops (Ω1 and Ω2) are numbered from the N to C terminus. (B) The CERT START domain in a complex with C16-ceramide. The ceramide molecule is represented as space-filling spheres in which yellow, blue, and red spheres represent C, N, and O atoms, respectively.
