Table 2.
Results of meta-analysis of the FACT-G raw scale scores
| Physical well-being | Functional well-being | Emotional well-being | Social well-being | Total FACT-G | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Number of contrasts | X | L | X | L | X | L | X | L | X | L |
| Trivial | 40 | 22 | 46 | 26 | 66 | 22 | 112 | 43 | 33 | 14 |
| Small | 97 | 32 | 97 | 36 | 122 | 61 | 95 | 42 | 77 | 37 |
| Medium | 85 | 33 | 81 | 30 | 44 | 9 | 15 | 1 | 83 | 27 |
| Large | 13 | 1 | 10 | 0 | 0 | 0 | 0 | 0 | 2 | 0 |
| Cross-sectional (X) | IWMD | 95% CI | IWMD | 95% CI | IWMD | 95% CI | IWMD | 95% CI | IWMD | 95% CI |
| Trivial | −0.09 | −2.2, 2.0 | 0.3 | −2.0, 2.7 | −0.16 | −1.5, 1.3 | 0.1 | −1.1, 1.4 | −1 | −8, 6 |
| Small | 1.9 | 0.6, 3.2 | 2.0 | 0.5, 3.5 | 1.0 | 0.1, 2.6 | 0.7 | −0.7, 2.1 | 6 | 2, 11 |
| Medium | 4.1 | 2.7, 5.5 | 3.8 | 2.0, 5.5 | 1.9 | 0.3, 3.5 | 0.8 | −2.9, 4.5 | 11 | 7, 15 |
| Large | 8.7 | 5.2, 12 | 8.8 | 4.3, 13 | – | – | – | – | 22 | −4, 48 |
| Longitudinal (L) | IWMD | 95% CI | IWMD | 95% CI | IWMD | 95% CI | IWMD | 95% CI | IWMD | 95% CI |
| Trivial | 0.5 | −1.1, 2.0 | −0.04 | −1.8, 1.7 | 0.3 | −1.1, 1.6 | 0.02 | −1.1, 1.1 | 0.4 | −5.5, 6.4 |
| Small | 0.8 | −0.4, 2.1 | 0.7 | −0.8, 2.2 | 1.1 | 0.3, 1.9 | 0.17 | −0.9, 1.2 | 2.4 | −1.4, 6.1 |
| Medium | 1.5 | 0.1, 2.9 | 1.5 | −0.2, 3.2 | 0.6 | −1.7, 2.8 | 0.06 | – | 3.3 | −1.3, 7.8 |
| Large | 8.2 | – | – | – | – | – | – | – | – | – |
Note: The scores are from all cross-sectional (X, n = 1,118) informative contrasts and longitudinal (L, n = 436) informative contrasts: number of contrasts and IWMD, with 95% CIs for the 5 FACT-G scales and the 4 size classes.
Abbreviations: FACT-G, Functional Assessment of Cancer Therapy-General; IWMDs, inverse-variance weighted mean differences; CIs, confidence intervals.