An exacerbation of COPD is characterised by a change in the patient’sbaseline dyspnoea, cough, and/or sputum production or colour |
Increased dyspnoea |
96 |
93–100 |
84–100 |
|
Increased sputum |
64 |
54–72 |
9–100 |
|
Increased purulence |
88 |
80–100 |
17–100 |
|
None of the symptoms |
0 |
0–4 |
0–13 |
|
Anthonisen Type I |
40 |
30–49 |
7–100 |
|
Anthonisen Type II |
26 |
19–32 |
0–50 |
|
Anthonisen Type III |
31 |
23–40 |
0–91 |
Diagnosis
|
Variable
|
Median
|
IRQ
|
Min-Max
|
For patients that require hospitalisation, measurement of arterial bloodgases is important to assess the severity of an exacerbation. |
Cases with a blood gas analysisin the emergency room |
95 |
88–100 |
33–100 |
|
Inspired oxygen concentrationrecorded in the ED |
93 |
73–100 |
0–100 |
Oxygen therapy
|
Variable
|
Median
|
IRQ
|
Min-Max
|
Oxygen therapy is the cornerstone of hospital treatment of COPDexacerbations and Supplemental oxygen should be titrated to improve thepatient’s hypoxemia |
Cases receiving oxygen duringadmission |
98 |
95–100 |
53–100 |
|
Pulse-oxymetry while receivingoxygen- therapy |
98 |
86–100 |
0–100 |
Bronchodilators
|
Variable
|
Median
|
IRQ
|
Min-Max
|
Management of COPD exacerbations involves increasing the doseand/or frequency of existing short-acting bronchodilator therapy, preferablywith a ß2 agonist. |
Cases on short-actingbronchodilators |
98 |
94–100 |
61–100 |
|
Cases on short-acting ß2 agonists |
93 |
85–97 |
11–100 |
|
Cases on ipratropium |
94 |
88–100 |
15–100 |
Antibiotics
|
Variable
|
Median
|
IRQ
|
Min-Max
|
Antibiotics should be given to patients with three cardinal symptoms,with two cardinal symptoms if purulence of sputum is one of the twosymptoms, and patients that require mechanical ventilation |
Cases on antibiotics withthree cardinal symptoms |
98 |
90–100 |
50–100 |
|
Cases on antibiotics with anincrease in sputum purulence |
97 |
91–100 |
0–100 |
|
Cases on ventilatorsupport receiving antibiotics |
100 |
83–100 |
0–100 |
Steroids
|
Variable
|
Median
|
IRQ
|
Min-Max
|
In the absence of significant contraindications oral corticosteroids shouldbe used, in conjunction with other therapies, in all patients admitted to hospitalwith an exacerbation of COPD. |
Cases on oral or intravenousglucocorticosteroids |
94 |
89–98 |
50–100 |
Discharge report
|
Variable
|
Median
|
IRQ
|
Min-Max
|
Opportunities for prevention of future exacerbations should be reviewedbefore discharge, with particular attention to smoking cessation, currentvaccination (influenza, pneumococcal vaccines), knowledge of current therapyincluding inhaler technique and how to recognize symptoms of exacerbations. |
Anti-tobacco instructions inactive smokers |
43 |
23–63 |
0–100 |
|
Influenza vaccination instructions |
0 |
0–7 |
0–100 |
|
Pneumococcal vaccinationinstructions |
0 |
0–3 |
0–100 |
|
Nutritional instructions |
37 |
21–53 |
0–100 |
|
Inhaler technique instructions |
7 |
0–19 |
02100 |
|
Programmed visit after discharge |
95 |
89–100 |
30–100 |