Table 2.
Genes up-regulated by hydrogen peroxide in Entamoeba histolytica HM-1:IMSS. The probe ID, accession number, description, baseline expression level, fold-change, p-value, and regulation under DPTA or other conditions are shown. The 30 most highly regulated genes are listed. HS (heat shock) (adapted from Hackney et al); Cysts (E. histolytica cysts) (adapted from Ehrenkaufer et al).
| Probe ID | Accession number | Description | Baseline expression level | Fold-change | p-value | Regulated under DPTA | Regulated under other conditions |
|---|---|---|---|---|---|---|---|
| 879.m00008_at | XM_642785 | hypothetical protein | 0.07 | 189.6 | 0.000 | - | - |
| 194.m00102_s_at | XM_645780 | hypothetical protein | 0.06 | 127.1 | 0.001 | + | HS |
| 654.m00032_x_at | XM_642891 | hypothetical protein | 1.39 | 114.9 | 0.023 | + | - |
| 363.m00049_x_at | XM_643869 | hypothetical protein | 0.17 | 89.05 | 0.015 | + | HS |
| 256.m00084_x_at | XM_644865 | hypothetical protein | 0.12 | 86.64 | 0.014 | + | HS |
| 256.m00083_x_at | XM_644864 | hypothetical protein | 1.22 | 82.85 | 0.014 | + | - |
| 692.m00024_s_at | XM_642872 | hypothetical protein | 0.05 | 76.14 | 0.000 | + | - |
| 248.m00060_s_at | XM_644979 | hypothetical protein | 0.05 | 71.78 | 0.000 | + | - |
| 266.m00066_s_at | XM_644755 | hypothetical protein | 0.13 | 53.25 | 0.002 | + | - |
| 194.m00123_x_at | XM_645776 | dUTP diphosphatase, putative | 0.11 | 50.95 | 0.011 | + | - |
| 397.m00055_s_at | XM_643659 | hypothetical protein | 0.18 | 42.56 | 0.020 | + | - |
| 654.m00031_s_at | XM_642894 | hypothetical protein | 0.06 | 41.05 | 0.000 | + | HS |
| 397.m00062_x_at | XM_643664 | hypothetical protein | 1.35 | 37.88 | 0.034 | + | - |
| 692.m00026_s_at | XM_642873 | hypothetical protein | 0.06 | 35.78 | 0.001 | + | - |
| 711.m00021_x_at | XM_642861 | hypothetical protein | 0.10 | 33.68 | 0.018 | + | HS |
| 375.m00057_x_at | XM_643790 | deoxyuridine 5 -triphosphate nucleotidohydrolase | 0.05 | 21.75 | 0.001 | + | - |
| 397.m00054_x_at | XM_643658 | hypothetical protein | 0.06 | 15.74 | 0.001 | + | - |
| 344.m00044_at | XM_644000 | hypothetical protein | 0.24 | 15.1 | 0.025 | + | - |
| 245.m00039_x_at | XM_645025 | hypothetical protein | 0.47 | 14.39 | 0.026 | + | Cysts |
| 219.m00107_at | XM_645351 | cell division control protein 42, putative | 0.10 | 11.34 | 0.003 | - | HS |
| 267.m00069_at | XM_644746 | hypothetical protein | 0.10 | 11.2 | 0.034 | - | - |
| 358.m00033_at | XM_643905 | hypothetical protein | 0.64 | 11.05 | 0.012 | + | Cysts |
| 194.m00103_at | XM_645781 | hypothetical protein | 0.07 | 10.44 | 0.005 | + | - |
| 8.m00393_at | XM_651687 | late competence protein, putative | 0.25 | 8.85 | 0.027 | - | HS + Cysts |
| 356.m00029_s_at | XM_643911 | hypothetical protein | 0.18 | 7.68 | 0.021 | + | HS |
| 20.m00272_at | XM_650868 | conserved hypothetical protein | 0.13 | 6.83 | 0.046 | + | - |
| 36.m00211_at | XM_650002 | hypothetical protein | 0.09 | 6.78 | 0.009 | + | Cysts |
| 35.m00253_at | XM_650038 | iron-sulfur flavoprotein, putative | 2.16 | 6.7 | 0.006 | - | Cysts |
| 312.m00037_at | XM_644279 | iron-sulfur flavoprotein, putative | 0.99 | 6.62 | 0.005 | - | HS + Cysts |
| 1.m00705_at | XM_652401 | BspA-like leucine rich repeat protein, putative | 0.27 | 6.56 | 0.004 | - | HS |